Study Highlight: Saffron and Mild-to-Moderate Postpartum Depression in Breastfeeding Mothers

 

Study Highlight: Saffron and Mild-to-Moderate Postpartum Depression in Breastfeeding Mothers

A double-blind, randomized, placebo-controlled clinical trial examined the effects of saffron stigma (Crocus sativus L.) in 60 breastfeeding mothers experiencing mild-to-moderate postpartum depression.

Study Design

Participants were divided into two groups:

• Saffron group: 15 mg twice daily
  • Total: 30 mg per day
• Placebo group

The treatment period lasted 8 weeks, and depression severity was measured using the Beck Depression Inventory-II (BDI-II), a commonly used clinical tool for assessing depressive symptoms.

Results

After 8 weeks, the saffron group showed a significantly greater reduction in depression scores compared with the placebo group.

Key findings included:

• 96% of women taking saffron achieved remission
• 43% of women in the placebo group achieved remission
• 66% of women in the saffron group showed a full clinical response
• Only 6% of women in the placebo group showed a full clinical response

Conclusion

The findings suggest that standardized saffron stigma, when used under clinical supervision, may be a promising option for mild-to-moderate postpartum depression in breastfeeding mothers.

Important Note

This does not mean saffron should be self-prescribed. Postpartum depression is a serious condition that requires professional evaluation and care. Anyone experiencing postpartum depression symptoms should speak with a qualified healthcare provider before trying supplements or herbal products.